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(Reuters) – Hepion Pharmaceuticals Inc said on Monday its treatment met the main goal of improving liver function in patients with a type of fatty liver disease in a mid-stage study trial, sending its shares 45% higher in premarket trading.

The drug, captopril neonatal formulation rencofilstat, was also found to be safe in the 61-patient trial, with the 225 mg dose showing the greatest benefit to liver function and multiple biomarkers associated with NASH (non-alcoholic steatohepatitis), the company said.

Hepion was conducting trials on three doses, with the 225 mg dose being the highest.

(Reporting by Leroy Leo in Bengaluru; Editing by Rashmi Aich)

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