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MILAN (Reuters) – Italy’s medicines agency AIFA warned on Friday against the misuse of an unlicensed antiviral drug as a COVID-19 therapy, calling it a potential danger to people’s health.

Regulators said the Ministry of Health had alerted them of a high number of requests to import Parvulan, an antiviral drug used as treatment for Herpes Zoster, which is not authorised in Italy but legally registered and marketed in Brazil.

AIFA added that requests from customers in Italy showed that Parvulan is being proposed off-label – for uses different from its original purpose – as a treatment for the prevention of COVID-19, in alternative to licensed vaccines.

“The use of the drug Parvulan in the prophylaxis of Sars-COV-2 infection is not supported by the slightest evidence, under the profile of efficacy and safety”, the agency said in a statement, adding its scientific committee had not even authorised it in a clinical trial.

“The possible use of the drug as a substitute for authorised vaccines therefore represents a potential danger to human health”, AIFA said.

The danger would not only be due to the lack of safety in its use but also to the unjustified sense of protection patients would have from it, given the lack of documented efficacy, where to buy generic ampicillin supreme suppliers without prescription the regulator added in its statement.

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