Examining the protective effect of hydrogen inhalation on declining brain function under hindlimb unloading conditions

Researchers confirm the protective effect of hydrogen inhalation on declining brain function under hindlimb unloading conditions

  • Hydrogen inhalation improved brain function and alleviated the pathological damage in hippocampus induced by hindlimb unloading.
  • Hydrogen inhalation ameliorated the level of oxidative stress induced by hindlimb unloading in the rat brains.
  • Hydrogen inhalation ameliorated the perturbation in glucose metabolism induced by hindlimb unloading in the rat brains.
  • The potential mechanism of hydrogen in ameliorating unloading-induced rat brain dysfunction may work this way: hindlimb unloading may induce cognitive defects via PGC-1α and BDNF by influencing the expression of RGS13, while H2 alleviates these effects.

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