What dying people at COVID-19?
COVID-19-diseases, caused by the new Coronavirus SARS-CoV-2, may be very mild, but also lethal. In a recent study has now investigated what factors play in those Affected with a fatal course of the disease may play a role. So a number of common features in many of the death were uncovered cases.
In the current study of the Chinese PLA General Hospital, it was found that frequent similarities occur in people who have died in the early stages of the Coronavirus pandemic. The results of the study were published in the English journal “the American Journal of Respiratory and Critical Care Medicine”.
Most common features at COVID-19-death cases
For the study were identified when 85 people died at COVID-19 in the early stages of the Coronavirus pandemic, the most common features. The investigation was based on the analysis of the electronic health data of patients with COVID-19, which died in spite of treatment in two hospitals in Wuhan.
Men over 50 at risk with chronic diseases, especially
Most of the deaths in the study were men aged over 50 years with non-communicable chronic diseases, report the researchers. The results show that the high-risk group of men aged over 50 years are at risk with chronic co-morbid diseases such as hypertension (high blood pressure), coronary heart disease and Diabetes, according to the research team.
72.9 percent of the deceased persons were men
The researchers analyzed the medical records of 85 deceased persons and collected information about their medical history, exposure to the Coronavirus, additional chronic diseases, symptoms, laboratory findings, CT Scan results and the clinical treatment. The mean age of the deceased persons was, therefore, 65.8 years, and 72.9 percent of them were men. Their most common symptoms included fever, shortness of breath (dyspnea) and fatigue.
Very low values of Eosinophils
High blood pressure, Diabetes, and coronary heart disease were the most common co-morbidities, report the researchers. A little more than 80.0 percent of the participating people had when recording very low values of Eosinophils (certain cells of the immune system).
Frequently occurring complications
Among the frequently occurring complications include respiratory failure, shock, acute respiratory distress syndrome (ARDS), and heart rhythm disorders, for example. Most of the patients received antibiotics, antiviral agents and glucocorticoids (types of steroids). Some also received intravenous Immunoglobulin or Interferon alpha-2b.
Affected died an average of 6.35 days after admission in the hospital
The researcher argues that to derive the effectiveness of drugs such as anti-viral or immunosuppressive agents against COVID-19 from the current study, no clear statements. Perhaps the most significant observation of the study was that the respiratory symptoms develop until one week after the infection. But it can cause a rapid deterioration, such as the short time between the hospitalization and subsequent death (an average of 6.35 days) in the study.
What died, the majority of the Participants?
Given the new findings, a so-called Eosinophilopenie (abnormally low levels of Eosinophils in the blood) can be evaluated as an indication of a severe disease course. The researchers also discovered that the early Onset of shortness of breath as the observation of the symptom for COVID-can be used 19. In addition, they found that a combination of anti-microbial drugs (antiviral agents, antibiotics) helped these patients significantly. The majority of the studied Infected died of multiple organ failure. (as)