Breakthroughs and challenges in fungal vaccine development

Breakthroughs and challenges in fungal vaccine development

What does a fungal vaccine need to prime an immune response?

Fungal cell wall antigens are key

Current fungal vaccine approaches

Live-attenuated or heat-killed whole cell vaccine

Recombinant subunit peptide or protein sequences

Antibody based vaccines

Commercialization and investment in fungal vaccines

Fungal vaccines are the future

  • Activating an effective antifungal immune response in at-risk, immunocompromised populations while mitigating undesirable side effects.
  • Advocating for government agencies to incentivize investment in fungal vaccine research and commercialization as a public health policy initiative.
  • Highlighting the economic impact a fungal vaccine will have as a preventative measure against fungal infections as climate change brings fungi to the forefront of environmental health.

Source: Read Full Article